Splenic dendritic cell subsets prime and boost CD8 T cells and are involved in the generation of effector CD8 T cells.

The ability of the dendritic cell (DC) subsets, CD8alpha+ and CD8alpha- DCs, to initiate a CD8 T cell response or to activate memory CD8 T cells and generate effector CD8 T cells has been controversial. In this study, we analyse the capacity of splenic DC subsets to induce CD8 T cell responses to a...

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Detalles Bibliográficos
Autores principales: Behboudi, S, Moore, A, Hill, A
Formato: Journal article
Lenguaje:English
Publicado: 2004