Epistasis can lead to fragmented neutral spaces and contingency in evolution.

In evolution, the effects of a single deleterious mutation can sometimes be compensated for by a second mutation which recovers the original phenotype. Such epistatic interactions have implications for the structure of genome space--namely, that networks of genomes encoding the same phenotype may no...

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Bibliographic Details
Main Authors: Schaper, S, Johnston, I, Louis, A
Format: Journal article
Language:English
Published: 2012