Identification and functional characterization of neo-poly(A) polymerase, an RNA processing enzyme overexpressed in human tumors.

Poly(A) polymerase (PAP) plays an essential role in polyadenylation of mRNA precursors, and it has long been thought that mammalian cells contain only a single PAP gene. We describe here the unexpected existence of a human PAP, which we call neo-PAP, encoded by a previously uncharacterized gene. cDN...

Full description

Bibliographic Details
Main Authors: Topalian, S, Kaneko, S, Gonzales, M, Bond, G, Ward, Y, Manley, J
Format: Journal article
Language:English
Published: 2001