Diastereoselective synthesis of 1,3,5-trisubstituted 4-nitropyrrolidin-2-ones via a nitro-Mannich/lactamization cascade.
A versatile one-pot nitro-Mannich/lactamization cascade for the direct synthesis of 1,3,5-trisubstituted 4-nitropyrrolidin-2-ones has been developed. The reaction is easy to perform and broad in scope, and high levels of diastereoselectivity can be achieved.
Λεπτομέρειες βιβλιογραφικής εγγραφής
| Κύριοι συγγραφείς: |
Pelletier, S,
Ray, P,
Dixon, D |
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| Μορφή: | Journal article
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| Γλώσσα: | English |
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| Έκδοση: |
2011
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