Cationic nioplexes-in-polysaccharide-based hydrogels as versatile biodegradable hybrid materials to deliver nucleic acids

Two polysaccharide-based hydrogels made of only κ-carrageenan (4%; w/v) or of a mixture of methylcellulose:κ-carrageenan (2%; w/v) were used to encapsulate cationic nioplexes. These vesicular particles were made of a synthetic aminolipid and polysorbate-80 (Tween-80), as a non-ionic surfactant agent...

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Bibliographic Details
Main Authors: Grijalvo, S, Alagia, A, Puras, G, Zárate, J, Mayr, J, Pedraz, J, Eritja, R, Díaz, D
Format: Journal article
Published: Royal Society of Chemistry 2017