Modeling the effects of transforming growth factor-beta on extracellular matrix alignment in dermal wound repair.

We present a novel mathematical model for collagen deposition and alignment during dermal wound healing, focusing on the regulatory effects of transforming growth factor-beta (TGFbeta.) Our work extends a previously developed model which considers the interactions between fibroblasts and an extracel...

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Bibliographic Details
Main Authors: Dallon, J, Sherratt, J, Maini, P
Format: Journal article
Language:English
Published: 2001