Insights into the mechanism of the cyanobactin heterocyclase enzyme

Cyanobactin heterocyclases share the same catalytic domain (YcaO) as heterocyclases/cyclodehydratases from other ribosomal peptide (RiPPs) biosynthetic pathways. These enzymes process multiple residues (Cys/Thr/Ser) within the same substrate. The processing of cysteine residues proceeds with a known...

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Bibliographic Details
Main Authors: Ge, Y, Czekster, C, Miller, O, Botting, C, Schwarz-Linek, U, Naismith, J
Format: Journal article
Language:English
Published: American Chemical Society 2019