Cellular and humoral mechanisms of osteoclast formation in Ewing's sarcoma.
Cellular mechanisms that account for tumour osteolysis associated with Ewing's sarcoma are uncertain. Osteoclasts are marrow-derived multinucleated cells (MNCs) that effect tumour osteolysis. Osteoclasts are known to form from macrophages by both receptor activator for nuclear factor-kappaB (RA...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2007
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