Cellular and humoral mechanisms of osteoclast formation in Ewing's sarcoma.

Cellular mechanisms that account for tumour osteolysis associated with Ewing's sarcoma are uncertain. Osteoclasts are marrow-derived multinucleated cells (MNCs) that effect tumour osteolysis. Osteoclasts are known to form from macrophages by both receptor activator for nuclear factor-kappaB (RA...

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Bibliographic Details
Main Authors: Lau, Y, Adamopoulos, I, Sabokbar, A, Giele, H, Gibbons, C, Athanasou, N
Format: Journal article
Language:English
Published: 2007