Cellular and humoral mechanisms of osteoclast formation in Ewing's sarcoma.
Cellular mechanisms that account for tumour osteolysis associated with Ewing's sarcoma are uncertain. Osteoclasts are marrow-derived multinucleated cells (MNCs) that effect tumour osteolysis. Osteoclasts are known to form from macrophages by both receptor activator for nuclear factor-kappaB (RA...
Autori principali: | Lau, Y, Adamopoulos, I, Sabokbar, A, Giele, H, Gibbons, C, Athanasou, N |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2007
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