Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene.

Chromosome 3 allele loss in preinvasive bronchial abnormalities and carcinogen-exposed, histologically normal bronchial epithelium indicates that it is an early, possibly the first, somatic genetic change in lung tumor development. Candidate tumor suppressor genes have been isolated from within dist...

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Detalhes bibliográficos
Principais autores: Xian, J, Clark, K, Fordham, R, Pannell, R, Rabbitts, T, Rabbitts, P
Formato: Journal article
Idioma:English
Publicado em: 2001