Intradermal cytosine-phosphate-guanosine treatment reduces lung inflammation but induces IFN-γ-mediated airway hyperreactivity in a murine model of natural rubber latex allergy.

Asthma and other allergic diseases are continuously increasing, causing considerable economic and sociologic burden to society. The hygiene hypothesis proposes that lack of microbial T helper (Th) 1-like stimulation during early childhood leads to increased Th2-driven allergic disorders later in lif...

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Bibliographic Details
Main Authors: Haapakoski, R, Karisola, P, Fyhrquist, N, Savinko, T, Wolff, H, Turjanmaa, K, Palosuo, T, Reunala, T, Lauerma, A, Alenius, H
Format: Journal article
Language:English
Published: 2011