MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation.

In the aftermath of thymic negative selection, natural and adaptive regulatory T cells (Tregs) must acknowledge peripheral, "danger-free" self-Ag to ensure their sustained activity. In this paper, we show that natural and adaptive Tregs or T cells transduced with cDNA for Foxp3, just like...

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Bibliographic Details
Main Authors: Howie, D, Nolan, K, Daley, S, Butterfield, E, Adams, E, Garcia-Rueda, H, Thompson, C, Saunders, N, Cobbold, S, Tone, Y, Tone, M, Waldmann, H
Format: Journal article
Language:English
Published: 2009