Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates

The rise of antibiotic resistance in many bacterial pathogens has been driven by the spread of a few successful strains, suggesting that some bacteria are genetically pre-disposed to evolving resistance. Here, we test this hypothesis by challenging a diverse set of 222 isolates of Staphylococcus aur...

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Bibliographic Details
Main Authors: Papkou, A, Hedge, J, Kapel, N, Young, B, Maclean, RC
Format: Journal article
Language:English
Published: Nature Research 2020