Novel adenovirus-based vaccines induce broad and sustained T cell responses to HCV in man

Currently, no vaccine exists for hepatitis C virus (HCV), a major pathogen thought to infect 170 million people globally. Many studies suggest that host T cell responses are critical for spontaneous resolution of disease, and preclinical studies have indicated a requirement for T cells in protection...

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Autors principals: Barnes, E, Folgori, A, Capone, S, Swadling, L, Aston, S, Kurioka, A, Meyer, J, Huddart, R, Smith, K, Townsend, R, Brown, A, Antrobus, R, Ammendola, V, Naddeo, M, O'Hara, G, Willberg, C, Harrison, A, Grazioli, F, Esposito, M, Siani, L, Traboni, C, Oo, Y, Adams, D, Hill, A, Colloca, S, Nicosia, A, Cortese, R, Klenerman, P
Format: Journal article
Idioma:English
Publicat: American Association for the Advancement of Science 2012