Using Phenotypic Heterogeneity to Increase the Power of Genome-Wide Association Studies: Application to Age at Onset of Ischaemic Stroke Subphenotypes

Using Phenotypic Heterogeneity to Increase the Power of Genome-Wide Association Studies: Application to Age at Onset of Ischaemic Stroke Subphenotypes

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Genome-wide association studies (GWAS) have been successful in identifying common variants related to complex disorders. However, some disorders have proved resistant to this strategy with few associations confirmed, despite evidence from twin and family studies of a genetic component. Sophisticated...

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Detalhes bibliográficos
Principais autores:	Traylor, M, Bevan, S, Rothwell, P, Sudlow, C, Dichgans, M, Markus, H, Lewis, C
Formato:	Journal article
Idioma:	English
Publicado em:	2013

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