Microbial-host co-metabolites are prodromal markers predicting phenotypic heterogeneity in behavior, obesity, and impaired glucose tolerance

The influence of the gut microbiome on metabolic and behavioral traits is widely accepted, though the microbiome-derived metabolites involved remain unclear. We carried out untargeted urine 1H-NMR spectroscopy-based metabolic phenotyping in an isogenic C57BL/6J mouse population (n = 50) and show tha...

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Detalhes bibliográficos
Principais autores: Dumas, M, Rothwell, A, Hoyles, L, Aranias, T, Chilloux, J, Calderari, S, Noll, E, Péan, N, Boulangé, C, Blancher, C, Barton, R, Gu, Q, Fearnside, J, Deshayes, C, Hue, C, Scott, J, Nicholson, J, Gauguier, D
Formato: Journal article
Idioma:English
Publicado em: Cell Press 2017