Persistent global inflammation caused by the loss of SIRT1 protects against experimental osteoarthritis

Persistent global inflammation caused by the loss of SIRT1 protects against experimental osteoarthritis

Inflammatory pathways have been attributed to play a central role in the pathogenesis of osteoarthritis (OA). However, most previous studies using knockout (KO) mice to inactivate inflammatory genes have showed no significant protection in experimental OA. In addition, biologic treatments targeting...

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Bibliographic Details
Main Authors:	Sacitharan, P, Zarebska, JM, Stott, BA, Parisi, I, Curtinha, MST, Bou-Gharios, G, Edwards, JR, Vincent, TL
Format:	Conference item
Published:	Elsevier 2017

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