Interferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease, characterised by increased expression of type I interferon (IFN)-regulated genes and a striking sex imbalance towards females. Through combined genetic, in silico, in vitro, and ex vivo approaches, we define CXorf21, a gene of hitherto unk...

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Bibliographic Details
Main Authors: Odhams, C, Roberts, A, Vester, S, Duarte, C, Beales, C, Clarke, A, Lindinger, S, Daffern, S, Zito, A, Chen, L, Jones, L, Boteva, L, Morris, D, Small, K, Fernando, M, Cunninghame Graham, D, Vyse, T
Format: Journal article
Language:English
Published: Nature Research 2019