Drivers of AR indifferent anti-androgen resistance in prostate cancer cells.

Inhibition of the androgen receptor (AR) by second-generation anti-androgens is a standard treatment for metastatic castration resistant prostate cancer (mCRPC), but it inevitably leads to the development of resistance. Since the introduction of highly efficient AR signalling inhibitors, approximate...

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Detalhes bibliográficos
Main Authors: Handle, F, Prekovic, S, Helsen, C, Van Den Broeck, T, Smeets, E, Moris, L, Eerlings, R, Kharraz, SE, Urbanucci, A, Mills, IG, Joniau, S, Attard, G, Claessens, F
Formato: Journal article
Idioma:English
Publicado em: Nature Research 2019