Critical importance of appropriate fixation conditions for faithful imaging of receptor microclusters

Receptor clustering is known to trigger signalling events that contribute to critical changes in cellular functions. Faithful imaging of such clusters by means of fluorescence microscopy relies on the application of adequate cell fixation methods prior to immunolabelling in order to avoid artefactua...

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Bibliographic Details
Main Authors: Stanly, T, Fritzsche, M, Banerji, S, García, E, Bernardino De La Serna, J, Jackson, D, Eggeling, C
Format: Journal article
Language:English
Published: Company of Biologists 2016