Mechanism based therapies enable personalised treatment of hypertrophic cardiomyopathy

Cardiomyopathies have unresolved genotype–phenotype relationships and lack disease-specific treatments. Here we provide a framework to identify genotype-specific pathomechanisms and therapeutic targets to accelerate the development of precision medicine. We use human cardiac electromechanical in-sil...

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Bibliographic Details
Main Authors: Margara, F, Psaras, Y, Wang, ZJ, Schmid, M, Doste, R, Garfinkel, AC, Repetti, GG, Seidman, JG, Seidman, CE, Rodriguez, B, Toepfer, CN, Bueno-Orovio, A
Format: Journal article
Language:English
Published: Springer Nature 2022