Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.
The MHC class I allele HLA-B27 is very strongly associated with development of autoimmune spondyloarthritis, although the disease mechanism remains unknown. Class I molecules classically associate in the endoplasmic reticulum (ER) with beta2-microglobulin (beta(2)m) and antigenic peptides for cell s...
主要な著者: | Bird, L, Peh, C, Kollnberger, S, Elliott, T, Mcmichael, A, Bowness, P |
---|---|
フォーマット: | Journal article |
言語: | English |
出版事項: |
2003
|
類似資料
-
Identification and characterisation of cell surface HLA-B27 homodimers
著者:: Bird, L, 等
出版事項: (2002) -
Cell-surface expression and immune receptor recognition of HLA-B27 homodimers.
著者:: Kollnberger, S, 等
出版事項: (2002) -
HLA-B27 transgenic rodents express cell surface HLA-B27 heavy chain homodimers and multimers.
著者:: Bowness, P, 等
出版事項: (2003) -
The pathogenesis of spondyloarthritides - HLA-B-27 homodimer expression on human monocyte/macrophage cell lines
著者:: McHugh, K, 等
出版事項: (2008) -
HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.
著者:: Kollnberger, S, 等
出版事項: (2004)