Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.

Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.

The MHC class I allele HLA-B27 is very strongly associated with development of autoimmune spondyloarthritis, although the disease mechanism remains unknown. Class I molecules classically associate in the endoplasmic reticulum (ER) with beta2-microglobulin (beta(2)m) and antigenic peptides for cell s...

Полное описание

Библиографические подробности
Главные авторы:	Bird, L, Peh, C, Kollnberger, S, Elliott, T, Mcmichael, A, Bowness, P
Формат:	Journal article
Язык:	English
Опубликовано:	2003

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