ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression.

ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression.

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The histone variant macroH2A generally associates with transcriptionally inert chromatin; however, the factors that regulate its chromatin incorporation remain elusive. Here, we identify the SWI/SNF helicase ATRX (α-thalassemia/MR, X-linked) as a novel macroH2A-interacting protein. Unlike its role i...

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מידע ביבליוגרפי
Main Authors: Ratnakumar, K, Duarte, L, LeRoy, G, Hasson, D, Smeets, D, Vardabasso, C, Bönisch, C, Zeng, T, Xiang, B, Zhang, D, Li, H, Wang, X, Hake, S, Schermelleh, L, Garcia, B, Bernstein, E
פורמט: Journal article
שפה:English
יצא לאור: 2012

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