ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression.
The histone variant macroH2A generally associates with transcriptionally inert chromatin; however, the factors that regulate its chromatin incorporation remain elusive. Here, we identify the SWI/SNF helicase ATRX (α-thalassemia/MR, X-linked) as a novel macroH2A-interacting protein. Unlike its role i...
Main Authors: | , , , , , , , , , , , , , , , |
---|---|
格式: | Journal article |
语言: | English |
出版: |
2012
|