ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression.
The histone variant macroH2A generally associates with transcriptionally inert chromatin; however, the factors that regulate its chromatin incorporation remain elusive. Here, we identify the SWI/SNF helicase ATRX (α-thalassemia/MR, X-linked) as a novel macroH2A-interacting protein. Unlike its role i...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2012
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ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression
Published 2012
Journal article