Splice-variant- and stage-specific RNA editing of the Drosophila GABA receptor modulates agonist potency.

The molecular diversity of many gene products functioning in the nervous system is enhanced by alternative splicing and adenosine-to-inosine editing of pre-mRNA. Using RDL, a Drosophila melanogaster GABA-gated ion channel, we examined the functional impact of RNA editing at several sites along with...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän: Jones, A, Buckingham, S, Papadaki, M, Yokota, M, Sattelle, B, Matsuda, K, Sattelle, D
Materialtyp: Journal article
Språk:English
Publicerad: 2009