A peptide-based vector for efficient gene transfer in vitro and in vivo.

Finding suitable nonviral delivery vehicles for nucleic acid-based therapeutics is a landmark goal in gene therapy. Cell-penetrating peptides (CPPs) are one class of delivery vectors that has been exploited for this purpose. However, since CPPs use endocytosis to enter cells, a large fraction of pep...

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Bibliographic Details
Main Authors: Lehto, T, Simonson, O, Mäger, I, Ezzat, K, Sork, H, Copolovici, D, Viola, JR, Zaghloul, E, Lundin, P, Moreno, P, Mäe, M, Oskolkov, N, Suhorutšenko, J, Smith, C, Andaloussi, SE
Format: Journal article
Language:English
Published: 2011