Specific cloning of DNA fragments absent from the DNA of a male patient with an X chromosome deletion.

A method that allows the specific cloning of DNA fragments absent from patients homozygous or hemizygous for chromosomal deletions is described. The method involves phenol-accelerated competitive DNA reassociation and subsequent molecular cloning of appropriately reassociated molecules. The deletion...

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Bibliographic Details
Main Authors: Kunkel, L, Monaco, A, Middlesworth, W, Ochs, H, Latt, SA
Format: Journal article
Language:English
Published: 1985