Targeting host-derived glycans on enveloped viruses for antibody-based vaccine design

The surface of enveloped viruses can be extensively glycosylated. Unlike the glycans coating pathogens such as bacteria and fungi, glycans on viruses are added and processed by the host-cell during biosynthesis. Glycoproteins are typically subjected to α-mannosidase processing and Golgi-mediated gly...

Полное описание

Библиографические подробности
Главные авторы: Crispin, M, Doores, K
Формат: Journal article
Язык:English
Опубликовано: Elsevier 2015