Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial

Patients with rheumatoid arthritis (RA) receive highly targeted biologic therapies without previous knowledge of target expression levels in the diseased tissue. Approximately 40% of patients do not respond to individual biologic therapies and 5–20% are refractory to all. In a biopsy-based, precisio...

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Bibliographic Details
Main Authors: Rivellese, F, Surace, AEA, Goldmann, K, Sciacca, E, Çubuk, C, Giorli, G, John, CR, Nerviani, A, Fossati-Jimack, L, Thorborn, G, Ahmed, M, Prediletto, E, Church, SE, Hudson, BM, Warren, SE, McKeigue, PM, Humby, F, Bombardieri, M, Barnes, MR, Lewis, MJ, Pitzalis, C
Other Authors: Taylor, PC
Format: Journal article
Language:English
Published: Springer Nature 2022