Aurora A promotes chromosome congression by activating the condensin-dependent pool of KIF4A

Aurora kinases create phosphorylation gradients within the spindle during prometaphase and anaphase, thereby locally regulating factors that promote spindle organization, chromosome condensation and movement, and cytokinesis. We show that one such factor is the kinesin KIF4A, which is present along...

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Autori principali: Poser, E, Caous, R, Gruneberg, U, Barr, F
Natura: Journal article
Lingua:English
Pubblicazione: Rockefeller University Press 2019