Aurora A promotes chromosome congression by activating the condensin-dependent pool of KIF4A

Aurora kinases create phosphorylation gradients within the spindle during prometaphase and anaphase, thereby locally regulating factors that promote spindle organization, chromosome condensation and movement, and cytokinesis. We show that one such factor is the kinesin KIF4A, which is present along...

ver descrição completa

Detalhes bibliográficos
Main Authors: Poser, E, Caous, R, Gruneberg, U, Barr, F
Formato: Journal article
Idioma:English
Publicado em: Rockefeller University Press 2019