Interplay of histone marks with serine ADP-ribosylation

Serine ADP-ribosylation (Ser-ADPr) is a recently discovered protein modification that is catalyzed by PARP1 and PARP2 when in complex with the eponymous histone PARylation factor 1 (HPF1). In addition to numerous other targets, core histone tails are primary acceptors of Ser-ADPr in the DNA damage r...

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Bibliographic Details
Main Authors: Bartlett, E, Bonfiglio, J, Prokhorova, E, Colby, T, Zobel, F, Ahel, I, Matic, I
Format: Journal article
Language:English
Published: Cell Press 2018