1.9 A structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen.

CAMPATH-1 antibodies have a long and successful history in the treatment of leukaemia, autoimmune disease and transplant rejection. The first antibody to undergo "humanisation", CAMPATH-1H, permits treatment with limited patient anti-globulin response. It recognises the CD52 antigen which...

Full description

Bibliographic Details
Main Authors: James, L, Hale, G, Waldmann, H, Bloomer, A, Waldman, H
Format: Journal article
Language:English
Published: 1999