1.9 A structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen.
CAMPATH-1 antibodies have a long and successful history in the treatment of leukaemia, autoimmune disease and transplant rejection. The first antibody to undergo "humanisation", CAMPATH-1H, permits treatment with limited patient anti-globulin response. It recognises the CD52 antigen which...
Үндсэн зохиолчид: | James, L, Hale, G, Waldmann, H, Bloomer, A, Waldman, H |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
1999
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Ижил төстэй зүйлс
Ижил төстэй зүйлс
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Crystal structures of a rat anti-CD52 (CAMPATH-1) therapeutic antibody Fab fragment and its humanized counterpart.
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Specificity of monoclonal antibody Campath-1.
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The CAMPATH-1 antigen (CDw52).
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Availability of Campath-1 antibodies for bone marrow transplantation.
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CAMPATH-1 monoclonal antibodies in bone marrow transplantation.
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