1.9 A structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen.
CAMPATH-1 antibodies have a long and successful history in the treatment of leukaemia, autoimmune disease and transplant rejection. The first antibody to undergo "humanisation", CAMPATH-1H, permits treatment with limited patient anti-globulin response. It recognises the CD52 antigen which...
المؤلفون الرئيسيون: | James, L, Hale, G, Waldmann, H, Bloomer, A, Waldman, H |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
1999
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مواد مشابهة
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Crystal structures of a rat anti-CD52 (CAMPATH-1) therapeutic antibody Fab fragment and its humanized counterpart.
حسب: Cheetham, G, وآخرون
منشور في: (1998) -
Specificity of monoclonal antibody Campath-1.
حسب: Hale, G, وآخرون
منشور في: (1988) -
The CAMPATH-1 antigen (CDw52).
حسب: Hale, G, وآخرون
منشور في: (1990) -
Availability of Campath-1 antibodies for bone marrow transplantation.
حسب: Hale, G, وآخرون
منشور في: (1995) -
CAMPATH-1 monoclonal antibodies in bone marrow transplantation.
حسب: Hale, G, وآخرون
منشور في: (1994)