1.9 A structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen.

CAMPATH-1 antibodies have a long and successful history in the treatment of leukaemia, autoimmune disease and transplant rejection. The first antibody to undergo "humanisation", CAMPATH-1H, permits treatment with limited patient anti-globulin response. It recognises the CD52 antigen which...

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Hlavní autoři: James, L, Hale, G, Waldmann, H, Bloomer, A, Waldman, H
Médium: Journal article
Jazyk:English
Vydáno: 1999