Evidence for abnormal Na+/H+ antiport activity detected by phosphorus nuclear magnetic resonance spectroscopy in exercising skeletal muscle of patients with essential hypertension.

1. Exercise-induced pH changes in skeletal muscle were studied in a group of eight subjects with essential hypertension by using 31P n.m.r. spectroscopy. 2. Leucocyte Na+/H+ antiport activity was measured in vitro in the same subjects using a pH-sensitive fluorescent dye. 3. Resting skeletal muscle...

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Bibliographic Details
Main Authors: Dudley, C, Taylor, D, Ng, L, Kemp, G, Ratcliffe, P, Radda, G, Ledingham, J
Format: Journal article
Language:English
Published: 1990