Beta-catenin abnormalities and associated insulin-like growth factor overexpression are important in phyllodes tumours and fibroadenomas of the breast.

The aim of this study was to assess the expression of IGF-I and IGF-II in phyllodes tumours and fibroadenomas and to see if there is any correlation between nuclear beta-catenin expression and IGF-I and IGF-II expression in these tumours. In a previous study, it has been shown that Wnt signalling is...

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Bibliographic Details
Main Authors: Sawyer, E, Hanby, A, Poulsom, R, Jeffery, R, Gillett, C, Ellis, I, Ellis, P, Tomlinson, I
Format: Journal article
Language:English
Published: 2003