Molecular action of sulphonylureas on KATP channels: a real partnership between drugs and nucleotides.
Sulphonylureas stimulate insulin secretion from pancreatic β-cells primarily by closing ATP-sensitive K(+) channels in the β-cell plasma membrane. The mechanism of channel inhibition by these drugs is unusually complex. As direct inhibitors of channel activity, sulphonylureas act only as partial ant...
| Egile Nagusiak: | , |
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| Formatua: | Journal article |
| Hizkuntza: | English |
| Argitaratua: |
Portland Press Limited
2015
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