Molecular action of sulphonylureas on KATP channels: a real partnership between drugs and nucleotides.

Molecular action of sulphonylureas on KATP channels: a real partnership between drugs and nucleotides.

Sulphonylureas stimulate insulin secretion from pancreatic β-cells primarily by closing ATP-sensitive K(+) channels in the β-cell plasma membrane. The mechanism of channel inhibition by these drugs is unusually complex. As direct inhibitors of channel activity, sulphonylureas act only as partial ant...

Detaylı Bibliyografya
Asıl Yazarlar:	de Wet, H, Proks, P
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	Portland Press Limited 2015

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