Computer-aided drug discovery of Myc-Max inhibitors as potential therapeutics for prostate cancer

While Myc is an essential regulator of growth in normal cells, it is also frequently associated with cancer progression, therapy-resistance and lethal outcomes in most human cancers. In prostate cancer (PCa), Myc transcription factors are implicated in the pathogenesis and progression of the full sp...

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Bibliographic Details
Main Authors: Carabet, L, Lallous, N, Leblanc, E, Ban, F, Morin, H, Lawn, S, Ghaidi, F, Lee, J, Mills, I, Gleave, M, Rennie, P, Cherkasov, A
Format: Journal article
Language:English
Published: Elsevier 2018