Recombination at mammalian telomeres: an alternative mechanism for telomere protection and elongation.

In human cells, homologous recombination (HR) provides an accurate mechanism for the repair of DNA double-strand breaks caused by replication fork breakdown or DNA damaging agents. HR also plays a role in the maintenance of eukaryotic telomeres; cells defective in the recombinational repair proteins...

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Detalles Bibliográficos
Autores principales: Tarsounas, M, West, S
Formato: Journal article
Lenguaje:English
Publicado: 2005