A dynamical framework for the all-or-none G1/S transition
The transition from G1 into DNA replication (S phase) is an emergent behavior resulting from dynamic and complex interactions between cyclin-dependent kinases (Cdks), Cdk inhibitors (CKIs), and the anaphase-promoting complex/cyclosome (APC/C). Understanding the cellular decision to commit to S phase...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Published: |
Elsevier
2016
|