Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei.
Known mechanisms of resistance to β-lactam antibiotics include β-lactamase expression, altered drug target, decreased bacterial permeability, and increased drug efflux. Here, we describe a unique mechanism of β-lactam resistance in the biothreat organism Burkholderia pseudomallei (the cause of melio...
Main Authors: | Chantratita, N, Rholl, D, Sim, B, Wuthiekanun, V, Limmathurotsakul, D, Amornchai, P, Thanwisai, A, Chua, H, Ooi, W, Holden, M, Day, N, Tan, P, Schweizer, H, Peacock, S |
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Format: | Journal article |
Language: | English |
Published: |
2011
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