A simple and fast two-locus quality control test to detect false positives due to batch effects in genome-wide association studies.

A simple and fast two-locus quality control test to detect false positives due to batch effects in genome-wide association studies.

The impact of erroneous genotypes having passed standard quality control (QC) can be severe in genome-wide association studies, genotype imputation, and estimation of heritability and prediction of genetic risk based on single nucleotide polymorphisms (SNP). To detect such genotyping errors, a simpl...

书目详细资料
Main Authors:	Lee, S, Nyholt, DR, Macgregor, S, Henders, A, Zondervan, K, Montgomery, G, Visscher, P
格式:	Journal article
语言:	English
出版:	2010

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