A simple and fast two-locus quality control test to detect false positives due to batch effects in genome-wide association studies.

The impact of erroneous genotypes having passed standard quality control (QC) can be severe in genome-wide association studies, genotype imputation, and estimation of heritability and prediction of genetic risk based on single nucleotide polymorphisms (SNP). To detect such genotyping errors, a simpl...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Lee, S, Nyholt, DR, Macgregor, S, Henders, A, Zondervan, K, Montgomery, G, Visscher, P
Aineistotyyppi: Journal article
Kieli:English
Julkaistu: 2010