Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial

<p><strong>Background:</strong>&nbsp;WHO recommends gametocytocidal, single low-dose primaquine for blocking the transmission of&nbsp;<em>Plasmodium falciparum</em>; however, safety concerns have hampered the implementation of this strategy in sub-Saharan Africa...

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Main Authors: Taylor, WR, Olupot-Olupot, P, Onyamboko, MA, Peerawaranun, P, Weere, W, Namayanja, C, Onyas, P, Titin, H, Baseke, J, Muhindo, R, Kayembe, DK, Ndjowo, PO, Basara, BB, Bongo, GS, Okalebo, CB, Abongo, G, Uyoga, S, Williams, TN, Taya, C, Dhorda, M, Tarning, J, Dondorp, AM, Waithira, N, Fanello, C, Maitland, K, Mukaka, M, Day, NJP
Format: Journal article
Language:English
Published: Elsevier 2022