Safety of age-dosed, single low-dose primaquine in children with glucose-6-phosphate dehydrogenase deficiency who are infected with Plasmodium falciparum in Uganda and the Democratic Republic of the Congo: a randomised, double-blind, placebo-controlled, non-inferiority trial
<p><strong>Background:</strong> WHO recommends gametocytocidal, single low-dose primaquine for blocking the transmission of <em>Plasmodium falciparum</em>; however, safety concerns have hampered the implementation of this strategy in sub-Saharan Africa...
Principais autores: | Taylor, WR, Olupot-Olupot, P, Onyamboko, MA, Peerawaranun, P, Weere, W, Namayanja, C, Onyas, P, Titin, H, Baseke, J, Muhindo, R, Kayembe, DK, Ndjowo, PO, Basara, BB, Bongo, GS, Okalebo, CB, Abongo, G, Uyoga, S, Williams, TN, Taya, C, Dhorda, M, Tarning, J, Dondorp, AM, Waithira, N, Fanello, C, Maitland, K, Mukaka, M, Day, NJP |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
Elsevier
2022
|
Registros relacionados
-
Factors affecting haemoglobin dynamics in African children with acute uncomplicated Plasmodium falciparum malaria treated with single low-dose primaquine or placebo
por: Onyamboko, MA, et al.
Publicado em: (2023) -
Pharmacokinetics of single low dose primaquine in Ugandan and Congolese children with falciparum malaria
por: Mukaka, M, et al.
Publicado em: (2023) -
Comparing HemoCue® and Quantitative Buffy Coat® and Coulter Counter-measured haemoglobin concentrations in African children with acute uncomplicated malaria: a Bland–Altman analysis
por: Ayuen, DS, et al.
Publicado em: (2025) -
PARIST study protocol: a phase I/II randomised, controlled clinical trial to assess the feasibility, safety and effectiveness of paracetamol in resolving acute kidney injury in children with severe malaria
por: Peter Olupot-Olupot, et al.
Publicado em: (2023-07-01) -
Epidemiology, clinical spectrum, and outcomes of severe malaria in Eastern Uganda: a prospective study
por: Cate Namayanja, et al.
Publicado em: (2025-02-01)